BIOVENTIX PLC Admission to PLUS-Quoted The directors of Bioventix plc ("Bioventix" or "the Company") are pleased to announce that the Company's entire issued ordinary share capital of 5,050,000 shares have been admitted to trading on PLUS-quoted today, 7 April 2010. In a separate announcement today, the Company is also announcing its interim financial results for the six months ended 31 December 2009. Bioventix (www.bioventix.com) specialises in the development and commercial supply of high-affinity monoclonal antibodies with a primary focus on their application in clinical diagnostics, such as in automated immunoassays used in blood testing. The antibodies created at Bioventix are generated in sheep and are of particular benefit where the target is present at low concentration and where conventional monoclonal or polyclonal antibodies have failed to produce a suitable reagent. Bioventix currently offers a portfolio of antibodies to customers for both commercial use and R&D purposes, for the diagnosis or monitoring of a broad range of conditions, including heart disease, cancer, fertility, thyroid function and drug abuse. Bioventix currently supplies antibody products and services to the majority of multinational clinical diagnostics companies. Ian Nicholson, Bioventix's Non-executive Chairman, said: "Bioventix has quietly established a profitable business developing high-affinity monoclonal antibodies targeting the multi-billion dollar clinical diagnostics market. The Directors now believe that the Company has reached an appropriate point in its development to seek a public listing for its shares, which will assist in raising the public profile of the Company, help to facilitate fund raising if required to finance future developments and also will enable the Company to pursue and fund strategic acquisitions, should such opportunities arise." Peter Harrison, CEO of Bioventix, said: "I am very proud of the progress that our team at Bioventix has made. We have built a profitable biotechnology business from a novel technology platform, which is a great achievement and I would like to thank everyone involved for their efforts. This new stage of the Company's evolution will hopefully herald continued growth and development of our business and the further creation of value for our shareholders." Key information Total number of Ordinary Shares in issue 5,050,000 immediately following Admission (par value 5p) Admission price 198p Market capitalisation £9,999,000 Sector classification Healthcare Principal activities Development and supply of antibodies PLUS symbol BVXP ISIN Number GB00B4QVDF07 PLUS Corporate Adviser Keith, Bayley, Rogers & Co. Limited ABOUT BIOVENTIX Bioventix was incorporated in 2003 following a management buyout of assets (including technology and intellectual property) relating to the creation of sheep monoclonal antibodies (SMAs) from KS Biomedix Limited. The management buyout was led by Peter Harrison and principally funded by SpringHill Bioventures Sendirian Berhad, a venture capital fund company registered and regulated by the Securities Commission in Malaysia. Since 2003, Bioventix has established a profitable commercial offering based on its SMA technology and it supplies a range of antibodies to multinational healthcare companies that manufacture machines for the clinical analysis of blood samples taken from patients. Antibodies form the basis of immunoassays used on these machines and, in some cases, SMAs have superior properties to other types of antibody. Such superiority might be manifest in the form of assay sensitivity (i.e. being able to measure a hormone at a lower concentration with greater precision) or assay specificity (i.e. being able specifically to measure a particular hormone and not be affected by another similar or related hormone). Bioventix's current portfolio of antibodies includes: * BVX.T3.17C6 (for use in FT3 testing; a thyroid hormone) * BVX.E2.5A11 (for use in estradiol testing; an important estrogen for fertility testing) * BVX.testo3.6A3 (for use in testing for testosterone levels; also for fertility) * BVX.THC.5B7 (for use in cannabis/marijuana; testing of saliva) * BVX.vitD2.2D12 (for use in testing for vitamin D deficiency) COMMERCIAL STRATEGY The total market for in-vitro diagnostics is estimated to be approximately 20 billion Euros. The market for immunodiagnostics represents a significant fraction of this and the market for antibodies that feature in these immunoassays represents a smaller sub-fraction of this market value. Bioventix's strategy is to identify new or existing commercial diagnostics assays for which there is or may be a need for improved antibodies, and to develop antibodies from its platform that offer superior clinical performance. The Directors anticipate that new assays will continue to be required or that the performance requirements of existing assays will be increased such that opportunities for new SMAs will emerge for the Company. Bioventix currently derives revenue from the following sources: 1. Sponsored antibody creation against designated clinical targets enabling customers exclusive access to the antibodies created under the contract. 2. Sales of purified antibodies for use on customers' blood-testing machines. 3. Product royalties from sales of a new diagnostic product based on an SMA developed by Bioventix. 4. Combination of sales of purified antibodies and product royalties BOARD OF DIRECTORS Ian Nicholson, BSc, MBA, aged 49, non-executive Chairman Ian Nicholson is the CEO of Chroma Therapeutics Limited, an emerging pharmaceutical company discovering and developing novel targeted oncology and inflammation drugs based on chromatin targets and its proprietary chemistry platform. Since moving to Chroma in late 2004, he has been successful in raising additional funds to support Chroma's product development pipeline. Ian was previously Senior Vice President of Business Development at Celltech Group plc, where he led the negotiations relating to Celltech's product alliances and several key technology acquisitions. He has held a variety of senior commercial positions with Oxford Asymmetry International plc, Lonza AG and Amersham International plc and has a BSc (Hons) degree from University College, London and an MBA from Boston University. Peter Harrison, MA, aged 51, Chief Executive Officer Peter Harrison has worked in the field of antibody technology since 1986 and has extensive experience of the development and commercialisation of antibody technologies. He graduated in Natural Sciences from Clare College Cambridge in 1980 and joined the graduate training scheme at Shell Chemicals UK Ltd. In 1986 he joined Celltech Ltd to manage the contract antibody production and in 1991 he joined KS Biomedix Ltd and helped to establish Sheep Monoclonal Antibody technology at their Farnham research laboratory. Following the acquisition of KS Biomedix Ltd by Xenova plc in 2003, he led a management buy-out that resulted in the formation of Bioventix and he has led the subsequent commercial development of the Company. Tim Cowper, ACA,aged 44, Finance Director Tim Cowper is a qualified Chartered Accountant with a wide range of experience working for private and public companies in the UK and the US. His experience includes Financial Controller roles at Sterilox Technologies Inc and at Celltech Group Plc and Director of Finance at Vernalis Plc (listed on the Official List) where he worked mainly on acquisitions, disposals and setting up operations in the US. Tim also held the position of Finance Director of Clipper Ventures Plc (formerly traded on AIM) and has been a director of certain family companies. In September 2008, Tim became a consultant with the FD Centre Limited where he acts as the part-time finance director for a range of companies, including Bioventix, on both interim assignments and longer term part-time engagements. Dr Kim Tan, BSc, PhD, aged 55, non-executive Director Dr Kim Tan is the founder Chairman of SpringHill Management Limited, a UK private equity and venture capital fund management company which provides certain management functions to SpringHill. He is also a director of SpringHill Management Sdn. Bhd, a Malaysian company, which is the fund manager for SpringHill. He is a former director of Active Capital Trust Plc, a UK listed investment trust company and the founder Chairman of AsiaPrise Biotech Sdn Bhd, which operates the NCI Cancer Hospital in Malaysia. Dr Tan is a director of a number of listed and private biotech and pharmaceutical companies in the UK, USA, South Africa and Malaysia and he is an adviser to a number of government agencies in Asia on biotechnology. He is also a board member of the Asia Pacific Economic Cooperation (APEC) Life Sciences Innovation Forum. He has a PhD in biochemistry and is a Fellow of the Royal Society of Medicine. Directors' current and past directorships held in the last five years Director Current Directorships/Partnerships Past Directorships/ Partnerships Ian Nicholson Bioindustry Association None Chroma Therapeutics Limited Macrotarg Limited Symphogen A/S Peter Harrison None None Tim Cowper Covelward Limited None TC Ventures Limited Kim Tan Alpha Biologics Sdn Bhn Active Capital Trust plc AsiaPrise Biotech Sdn Bhd Jubilee Action Connect 2 Innovation Limited Marksans Pharma Limited Inqo Investments (Pty) Limited Reliance Genemedix plc MEC Dynamics Corp Saracens Limited Progenix Research Sdn Bhn Tranxenogen Limited Springhill Management Limited SpringHill Management Sdn Bhd Transformational Business Network Transformational Business Network Foundation DIRECTORS' INTERESTS AND SUBSTANTIAL SHAREHOLDER Directors Name No. of Ordinary % of Issued Share Shares Capital Ian Nicholson 50,000 0.99% Peter Harrison 1,000,000 19.8% Tim Cowper - - Kim Tan - - Substantial Shareholder Name No. of Ordinary % of Issued Share Shares Capital SpringHill Bioventures Sendirian 3,500,000 69.31% Berhad As a director of SpringHill Management Sdn Bhd, the fund manager for SpringHill Bioventures Sdn Bhd, Dr Tan exercises SpringHill Bioventures' voting rights in Bioventix plc under the authority given by SpringHill Bioventures to the fund manager. The Directors of Bioventix plc accept responsibility for this announcement. CONTACTS Bioventix plc Peter Harrison, CEO +44 (0)1252 728001 Keith, Bayley, Rogers & Co. Limited David Coffman +44 (0)203 100 8300 Citigate Dewe Rogerson Chris Gardner or Mark Swallow +44 (0)207 282 2995 / +44(0)207 282 2948 END
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