LEXINGTON, Mass. and AMSTERDAM, the Netherlands, 2017-04-24 22:05 CEST (GLOBE NEWSWIRE) -- uniQure N.V. (NASDAQ:QURE), a leading gene therapy company advancing transformative therapies for patients with severe medical needs, today announced that five abstracts have been accepted for presentation at the American Society of Gene and Cell Therapy (ASGCT) 20th Annual Meeting held in Washington, D.C., May 10-13, 2017. Together with their collaborators, members of uniQure's research and development team will present data focused on progress in re-administration protocols, gene therapy delivery systems and optimized vector distribution technologies in two of uniQure's key programs, hemophilia B and Huntington's disease. An investor and analyst breakfast meeting featuring senior members of uniQure's research and development team will be held on Friday, May 12 at 7 a.m.
"The data to be presented at the ASGCT meeting demonstrate the development and validation of uniQure's technologies to improve gene therapy as a therapeutic approach, and supports our aim to rapidly bring new disease-modifying therapies to patients with severe genetic diseases," stated Matthew Kapusta, chief executive officer of uniQure.
Harald Petry, Ph.D., chief scientific officer at uniQure, added, "We are making strong progress in advancing the preclinical development of AMT-130 in Huntington's disease, and further enhancing AAV vector technology and the potential for re-administration protocols, which continue to provide compelling evidence of our modular platform."
Specific details on uniQure's presentations at ASGCT include:
-- Title: Novel AAV Vector Reservoirs: peripheral Blood Cells and Hematopoietic Progenitors. (collaborator presentation) Oral Session Title: AAV Vector Biology Date and Time: Wednesday, May 10, 2017, 10:30 a.m. EDT Location: Marriott Salon 1 -- Title: Circulating Anti-AAV5 Neutralizing Antibody Titers up to 1:1031 Do Not Affect Liver Transduction Efficacy of AAV5 Vectors in Non-Human Primates (Poster 198). Poster Session Title: Immunological Aspects of Gene Therapy and Vaccines I Session Date and Time: Wednesday, May 10, 2017, 5:30 - 7:30 p.m. EDT Location: Hall A&B South -- Title: Successful Repeated Hepatic Gene Delivery in Non-Human Primates Achieved with AAV5 by Use of Immune Adsorption (Poster 395). Poster Session Title: Immunological Aspects of Gene Therapy and Vaccines II Session Date and Time: Thursday, May 11, 2017, 5:15 - 7:15 p.m. EDT Location: Hall A&B South -- Title: AAV5-miHTT Gene Therapy Demonstrates Broad Vector Distribution and Strong Mutant Huntingtin Lowering in a Huntington's Disease Minipig Model. Oral Session Title: Preclinical Progress Towards Therapies for Neurologic Disorders Date and Time: Friday, May 12, 2017, 4:30 p.m. EDT Location: Delaware AB -- Title: Detection of AAV Vector DNA and Transgene RNA in Liver Tissue by Fluorescent In Situ Hybridization (Poster 567). Poster Session Title: AAV Vectors III Session Date and Time: Friday, May 12, 2017, 5:45 - 7:45 p.m. EDT Location: Hall A&B South
Investor and Analyst Breakfast uniQure management will host an investor and analyst breakfast meeting featuring members of the research and development team to review the data presented during ASGCT.
Date and Friday, May 12, 2017 at 7:00 am EDT Time: Location: Omni Shoreham Hotel, The Congressional Room, 2500 Calvert Street NW, Washington, DC. The Omni Shoreham hotel is located directly across the conference venue.
To request attendance at the meeting, please RSVP to Investors@uniQure.com by May 5, 2017, as space is limited.
About uniQure uniQure is delivering on the promise of gene therapy - single treatments with potentially curative results. We are leveraging our modular and validated technology platform to rapidly advance a pipeline of proprietary and partnered gene therapies to treat patients with liver/metabolic, central nervous system and cardiovascular diseases. www.uniQure.com
uniQure Forward-Looking Statements This press release contains forward-looking statements. All statements other than statements of historical fact are forward-looking statements, which are often indicated by terms such as "anticipate," "believe," "could," "estimate," "expect," "goal," "intend," "look forward to", "may," "plan," "potential," "predict," "project," "should," "will," "would" and similar expressions. Forward-looking statements are based on management's beliefs and assumptions and on information available to management only as of the date of this press release. These forward-looking statements include, but are not limited to, statements regarding the development of our gene therapy product candidates. Our actual results could differ materially from those anticipated in these forward-looking statements for many reasons, including, without limitation, risks associated with collaboration arrangements, our and our collaborators' clinical development activities, regulatory oversight, product commercialization and intellectual property claims, as well as the risks, uncertainties and other factors described under the heading "Risk Factors" in uniQure's 2016 Annual Report on Form 10-K filed with the Securities and Exchange Commission on March 15, 2017. Given these risks, uncertainties and other factors, you should not place undue reliance on these forward-looking statements, and we assume no obligation to update these forward-looking statements, even if new information becomes available in the future.
uniQure Contacts: Maria E. Cantor Direct: 339-970-7536 Mobile: 617-680-9452 m.cantor@uniQure.com Eva M. Mulder Direct: +31 20 240 6103 Mobile: +31 6 52 33 15 79 e.mulder@uniQure.com Tom Malone Direct: 339-970-7558 Mobile: 339-223-8541 t.malone@uniQure.com
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